I learned a new word today: deprescription. It apparently refers to the act of stopping a prescribed drug.
There’s a class of type 2 diabetes drugs called GLP-1 receptor agonists. Popular examples are Ozempic and Trulicity. They help users to lose excess weight. But there’s concern about long-term drug side effects regain of lost weight when the drug is stopped. So do successful users need to take the drug lifelong?
A study published earlier this year in Diabetes Therapy suggests that successful users of GLP-1 receptor agonists can stop the drug without weight regain and without loss of diabetes control if they also adhere to a very carbohydrate restricted diet. How much carb restriction? Under 30 grams/day, at least at first. That’s going to be ketogenic in most folks. Although I don’t recall seeing “ketogenic” in the study at hand.
Steve Parker, M.D.
Paleo Diabetic 