Many physicians and dietitians have been hesitant to suggest ketogenic diets due to 1) possible increased risk of cardiovascular disease, and 2) unknown effects on overall mortality.
But a study published at Scientific Reports in October 2024 suggests that ketogenic diets reduce overall mortality by 24% with no effect on cardiovascular-related deaths. Click the link to see the full report. I haven’t read it yet. Don’t ask me what “restricted cubic spline function” means!
The paleo diet can be ketogenic after a few modifications that get total daily digestible carbs down to 20-30 grams/day. That can be very risky for diabetics taking insulin or other drugs with potential to cause hypoglycemia. But the risk is manageable with medical supervision.
Steve Parker, M.D.
Paleo Diabetic 