How to Detox From Nanoplastics

Free pile plastic bottles image“/ CC0 1.0

Scott Gavura over at Science-Based Medicine writes about the desire to detoxify our bodies periodically:

Headlines about plastic particles being detected in blood, lungs, placentas, and other tissues have been rapidly assimilated into the wellness ecosystem. Microplastics are tiny plastic particles that come from the breakdown of larger plastic pieces. Because microplastics are ubiquitous, persistent and easily dispersed, they are found in water, food and air – and our bodies. While their impact on human health continues to be studied, the message from wellness entrepreneurs has been simplified to: Plastics are accumulating inside you, and are causing you harm.

This is the perfect setting for detox marketing. Much like the Candida detox kits popular 20 years ago, supplements, binders, sauna protocols, and “plastic detox” programs now claim to remove microplastics (instead of yeast) from the body or reduce an individual’s “plastic burden.” Some businesses and clinics offer testing panels that purport to measure retained plastics, despite the absence of validated methods to do so in a clinically meaningful way. Unlike Candida, microplastics are a real environmental and health issue worthy of study. And that’s happening. But, just like older detox trends, a real scientific issue is already being used to justify claims that go far beyond the evidence.

What’s missing from the marketing claims is any evidence that these detox interventions actually work. Detecting microplastics in human tissues does not automatically imply that they can be selectively removed, or that proposed detox strategies meaningfully alter health outcomes. There is no credible evidence that supplements, saunas, chelation-like binders, or dietary protocols can “flush” plastics from the body. The leap to offering a personal detox solution is marketing, not evidence-based medicine.

The microplastics detox narrative we’re seeing also exploiting a familiar (and recurrent) misunderstanding of toxicology: the assumption that detection equals danger, and that identification necessitates purging. In reality, …

Scott is justifiably skeptical about microplastics detoxification protocols. The time may come we can rid ourselves of this contamination. But it’s not now.

Steve Parker, M.D.

Dr Michael Yeadon: Reflections on the Pandemic

Regarding COVID-19 vaccines, LifeSite News reports that  former Pfizer vice president and chief scientist for allergy and respiratory Dr. Michael Yeadon has concluded that someone with his expertise was directed to “…design injections that will injure, kill, and reduce fertility in the people you give it to. And design it so that it won’t kill everybody, it won’t injure everybody, but if we give it to enough people over time it will lower the fertility and their health and reduce population.”

The article states that Dr Yeadon believes that putting COVID-19 patients on ventilators caused adult respiratory distress syndrome (ARDS). All the ventilator patients I saw had ARDS before they were ever put on ventilators.

I have a few other bones to pick with Dr Yeadon. He says there was no pandemic. The year 2020 undoubtedly saw a high number of respiratory deaths worldwide from what seemed to be an infection by a virus, whether it was COVID-19 or some other virus. Dr Y believes ventilators were used excessively and too early in the course of illness. I didn’t see that in my hospital. We used them in patients in extreme respiratory distress with sustained high respiratory rates (e.g., 60 breaths/minute) who we thought were likely to quit breathing soon if we did nothing. Putting them on the ventilator was often the only option we had left. Dr Y also is convinced that the drug treatment called remdesivir (“run, death is near”) was worthless. If memory serves, the World Health Organization in 2020 decreed the same thing. Yet there were professional societies of infectious disease specialists who thought it was useful. Either way, I’m not sure.

—–Steve Parker, M.D.

Oh Great…One More Thing to Worry About!: Microplastics

It’s getting harder for me to ignore microplastics. They contaminate our water, food, soil, oceans, and air. The guy in this video says the average adult brain contains as much invasive plastic as a typical plastic fork (5 grams?). These plastics are said to cause medical problems although I’m not sure of the strength of the evidence. Very few physicians know about this issue. The video speaker below talks about nanoplastics but in my experience “microplastics” is more often used. Something nano would be smaller than micro, a thousand times smaller if we’re using the metric system. Colloquially, nano may just be “quite a bit smaller” than micro. YouTube posted the video Dec 3, 2025:

The speaker refers to a scientific article published at Nature Medicine on Feb 3, 2025: Bioaccumulation of microplastics in decedent human brains. Seems to me they should have used “nanoplastics” in the title instead of “microplastics.”

Not only are the microplastics allegedly bad for us, they are linked to “forever chemicals” which may mediate the badness. E.g., BPA-like chemicals (bisphenol A).

Katie Couric interviewed Dr. Matthew J Campen, one of the authors of the study referenced above and a toxicology professor at the University of New Mexico. He impresses me with the idea that his study’s findings are very preliminary and need verification by other labs, and that the implications for how we live today are not clear by any means. He speculates that the nanoplastics he finds in human tissue samples were ingested as nanoparticles that originated in landfills years ago. Discarded plastic waste deteriorated over time, breaking down to nanoparticles that contaminated groundwater and also ended up in agricultural products. Therefore, he suggests that there is not much individuals can do about avoiding nanoplastics except perhaps limiting meat consumption. Dr Campen notes that cutting down on our use of plastics now is more likely to help those a couple generations hence than to help us. He is highly skeptical about any current remedies that purport to remove nanoplastics from our tissues. Yet he suggests that our bodies may indeed have an intrinsic mechanism to reject (eject?) the particles.

Are you worried about microplastics in your body?

Click this link to NRDC (National Resources Defense Council) for ten tips to keep plastic out of your body.

Steve Parker, M.D.

Basic Science Lecture: How Do Ozempic, Zepbound, Wegovy, and Mounjaro Work?

This alleged pathologist explains how drugs like Ozempic, Zepbound, Wegovy, and Mounjaro work to reduce appetite and lead to weight loss. Which could help if you have type 2 diabetes. These drugs are analogs of either GLP-1 (glucose-like peptide-1) or GIP (glucose-dependent insulinotropic polypeptide), or a combination of both.

The doctor gets pretty technical. Click for a simpler explanation from UCHealth.

These drugs make me think of the 1970s TV add for Chiffon margarine telling us “It’s not nice to fool Mother Nature.”

Steve Parker, M.D.

PS: Diet modification is also critical for management of type 2 diabetes.

The Dilemma of Medical Journal Integrity

When I was doing my Internal Medicine residency in 1981 to 1984, we held scientific medical journals in great esteem. The New England Journal of Medicine, for instance. It was published once weekly, about a hundred pages IIRC. At the end of the year, I sent my 52 copies off to a bindery to be glued into a hard-cover book format, to be cherished and consulted for years. That book was two or three inches thick. I did that for maybe five consecutive years; I’ve no idea where they are now. Probably in a landfill.

The told us on the first day of medical school, “Half of what we teach you will be obsolete in five years.” So continuing medical education is an imperative. One potential way to keep learning is to read medical journals.

You may be surprised to learn that I no longer read scientific medical journals very often. How do I keep my medical practices up to date? I work in the hospital side-by-side with surgeons and medical subspecialists (e.g., cardiologists, gastroenterologists). In general, I talk to them and watch what they do. If there is a ground-breaking new diagnostic tool or therapy, I’ll hear about it from them. They’re not in an ivory tower, isolated from patients. They’re in the trenches with me facing sick and hurting patient every day. I still read scientific medical journals, but take them with a nugget of salt.

I’m a science journal skeptic, questioning their reliability, objectivity, and relevance. By far, I’m not the only won. Check out the writings of Dr. Marcia Angell, former editor of New England Journal of Medicine, and Dr. John Ioannidis.

Seemay Chou had this to say about scientific journals:

I’m a scientist. Over the past five years, I’ve experimented with science outside traditional institutes. From this vantage point, one truth has become inescapable. The journal publishing system — the core of how science is currently shared, evaluated, and rewarded — is fundamentally broken. 

Vox Day has excerpted a TLDR from Chou’s article:

It might seem like publishing is a detail. Something that happens at the end of the process, after the real work of science is done. But in truth, publishing defines science.

The currency of value in science has become journal articles. It’s how scientists share and evaluate their work. Funding and career advancement depend on it. This has added to science growing less rigorous, innovative, and impactful over time. This is not a side effect, a conspiracy, or a sudden crisis. It’s an insidious structural feature.

For non-scientists, here’s how journal-based publishing works:

After years of research, scientists submit a narrative of their results to a journal, chosen based on field relevance and prestige. Journals are ranked by “impact factor,” and publishing in high-impact journals can significantly boost careers, visibility, and funding prospects.

Journal submission timing is often dictated by when results yield a “publishable unit” — a well-known term for what meets a journal’s threshold for significance and coherence. Linear, progressive narratives are favored, even if that means reordering the actual chronology or omitting results that don’t fit. This isn’t fraud; it’s selective storytelling aimed at readability and clarity.

Once submitted, an editor either rejects the paper or sends it to a few anonymous peer reviewers — two or three scientists tasked with judging novelty, technical soundness, and importance. Not all reviews are high quality, and not all concerns are addressed before editorial acceptance. Reviews are usually kept private. Scientific disagreements — essential to progress — rarely play out in public view.

If rejected, the paper is re-submitted elsewhere. This loop generally takes 6–12 months or more. Journal submissions and associated data can circulate in private for over a year without contributing to public discussion. When articles are finally accepted for release, journals require an article processing fee that’s often even more expensive if the article is open access. These fees are typically paid for by taxpayer-funded grants or universities.

Several structural features make the system hard to reform:

  • Illusion of truth and finality: Publication is treated as a stamp of approval. Mistakes are rarely corrected. Retractions are stigmatized.
  • Artificial scarcity: Journals want to be first to publish, fueling secrecy and fear of being “scooped.” Also, author credit is distributed through rigid ordering, incentivizing competition over collaboration. In sum, prestige is then prioritized.
  • Insufficient review that doesn’t scale: Three editorially-selected reviewers (who may have conflicts-of-interest) constrain what can be evaluated, which is a growing problem as science becomes increasingly interdisciplinary and cutting edge. The review process is also too slow and manual to keep up with today’s volume of outputs.
  • Narrow formats: Journals often seek splashy, linear stories with novel mechanistic insights. A lot of useful stuff doesn’t make it into public view, e.g. null findings, methods, raw data, untested ideas, true underlying rationale.
  • Incomplete information: Key components of publications, such as data or code, often aren’t shared to allow full review, reuse, and replication. Journals don’t enforce this, even for publications from companies. Their role has become more akin to marketing.
  • Limited feedback loops: Articles and reviews don’t adapt as new data emerges. Reuse and real-world validation aren’t part of the evaluation loop. A single, shaky published result can derail an entire field for decades, as was the case for the Alzheimer’s scandal.

Stack all this together, and the outcome is predictable: a system that delays and warps the scientific process. It was built about a century ago for a different era. As is often the case with legacy systems, each improvement only further entrenches a principally flawed framework.


Steve Parker, M.D.

My Confession of Medical Heresy

Heart attacks and chest pains are linked to blocked arteries in the heart

It was around 2009 when I was prepared to abandon the time-honored diet-heart hypothesis. I remember wondering if I’d be excommunicated from the medical community, i.e., lose my medical license due heresy. In a nutshell, the diet-heart hypothesis to which I refer was the idea that dietary saturated fat was the clear-cut cause of coronary artery disease and associated angina pectoris, heart attacks, and cardiac deaths. And many strokes, too.

My re-evaluation of the evidence paved the way to my Paleobetic diet.

Dr. Axel Sigurdsson recently wrote an updated history of the diet-heart hypothesis, focusing on the downfall of the hypothesis and the role of George Mann, whom I’d swear I never herd of. An excerpt:

Ancel Keys changed the world. He was right about many things—that lifestyle matters, that food affects disease, that public health can’t afford to wait forever. But in boiling heart disease down to a single nutrient, he oversimplified a complex truth. His hypothesis became policy before it was fully proven. And once policy hardens, it resists correction.

George Mann was no savior. His critiques were often bombastic, his tone combative. But beneath the fire was a warning science should have heeded: that premature consensus can blind, that evidence must lead—not politics, not personalities, not the noise of institutional momentum.

I recommend the entire article to you. I suspect AI (artificial intelligence) was utilized, mainly judging from the three pictures. Dr. Sigurdsson has been publishing some great articles recently, and I believe credited AI in some of them, which is OK by me.

Steve Parker, M.D.

COVID Vaccine Link to Neuropsychiatric Disorders

COVID-19 Vaccination Sites” by U.S. Navy Medicine/ CC0 1.0

Alleged attorney Jeff Childers reports an alleged link between the covid-19 vaccine(s) and neuropsychiatric disorders. The item starts a third of the way down the web page. I haven’t read the source article and probably won’t. You’ll see mention below of cerebral venous sinus thrombosis. One of the neurologists I work with has started ordering more brain scans looking for that. Coincidence?

All that follows is from Childers. To facilitate readability, I won’t put it in italics like I usually do quotations:

For years, scientists who questioned mRNA safety were told to put up or shut up (“publish or perish”). Well— now they’ve published. And I’ll give you one guess whether or not the conclusions support our long-standing concerns. Today, a new peer-reviewed study published in the International Journal of Innovative Research in Medical Science, blandly titled “View of Association Between COVID-19 Vaccination and Neuropsychiatric Conditions.

image 10.png

The results, however, were not bland.

In the just-published peer-reviewed study, researchers analyzed over three decades of vaccine injury reports in the U.S. government’s own VAERS database, comparing covid mRNA vaccines to both flu shots and all other vaccines (combined). Using the CDC’s and FDA’s own method for detecting safety problems —called “Proportional Reporting Ratios” or PRRs— they found that reports of serious neuropsychiatric issues like brain fog, psychosis, dementia, and even suicidal behavior were not just higher, but dozens to hundreds of times more frequent after the covid shots.

If you thought people were crazy to take the jab, you might have been onto something.

The safety signal thresholds weren’t just crossed; they were blown out of the water, with some categories showing PRRs over four hundred, far above the FDA’s red-flag threshold of two. The study concluded these signals were sufficiently alarming to warrant immediate attention and further investigation— an understatement as big as the Statue of Liberty.

Among the most alarming findings, the study flagged massive spikes in reports of serious brain-related problems after covid vaccination. Compared to flu shots, reports of brain fog were up over 100-fold, psychosis nearly 80 times higher, and Alzheimer’s-type dementia more than 40 times more frequent. Even more chilling, reports related to suicidal thoughts or behaviors, including suicide attempts and self-harm, showed increases as high as 80-fold. One rare but deadly condition —cerebral venous sinus thrombosis, a type of brain clot— was reported at rates over 400 times higher than with flu vaccines.

These numbers weren’t small deviations— they were sky-high red flags by the FDA’s own data and safety standards.


Steve Parker, M.D.

RIP: Dr Richard Bernstein, Modern Diabetes Pioneer

Dr Bernstein passed on to his reward last April. He was a major influence on my own approach to diabetes treatment. We see very few “great men” in our times: He was one.

Dr Bernstein practiced what he preached, which explains how he lived to the age of 90. That is exceedingly rare for a type 1 diabetic.

Thanks to Jan at The Low Carb Diabetic for bringing this to my attention. She published an account of what it was like to be one of Dr Bernstein’s patients.

Steve Parker, M.D.

Why Does Eliquis Cost $8,000 in the U.S. But Only $700 in Germany?

From Karl Denninger, an article titled Enough of this Nonsense:

I’m talking about the basic economic question: Supply, demand and what happens when you allow someone to force another person to pay your bill.

I keep hammering on this and will until people stop running tropes whether out of sincere (but false) belief or some other reason.

Let’s take Eliquis.  Its a common medication and its expensive.  Roughly 3.5 million Americans take this drug and it is one of the most-commonly prescribed for people who have atrial fibrillation.  It appears to be reasonably effective in reducing the risk of strokes and heart attacks in people with that condition.

It is also about $8,000 a year in the United States without insurance and “insurance” forces those who do not have that condition to pay for those who do — including Medicare and Medicaid.

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The common claim is that “if you cut that off those people will die” because they can’t possibly afford the price.

The claim is false.

In Germany the drug costs about $700 a year, so it is ten times as expensive in the United States.


Parker here. I know why Eliquis (apixaban) so much more expensive in the U.S. I wrote all about it in my latest book. Read Denninger for his opinion. (He’s smarter than me but was wrong about his predicted 2024 severe economic contraction. Making predictions is hard, especially when it’s about the future.)

Steve Parker, M.D.

Health Insurance Pre-Authorizations Soon to Be Relegated to the Dustbin of History

Steve Parker MD, eye chart, eye exam
Macular degeneration is the opposite of this: blacked-out or fuzzy vision in the center, clearer at the periphery

I’ll believe it when I see it.

Health insurance pre-authorization, for example, is when your eye specialist recommends removal of your cataracts so you can see again, but your insurance company wants some clerk or administrator to review everything and either agree or disagree with your physician. If disagree, no eye surgery for you. Unless you’re willing to pay entirely out-of-pocket. Mind you, the clerk does not have a medical degree and has never examined you or spoken to you. Isn’t this one of the reasons Luigi Mangione executed that healthcare executive?

From American Greatness:

Health and Human Services (HHS) Secretary Robert F. Kennedy Jr. joined other federal health officials on Monday to promote an initiative to end the practice of healthcare insurance pre-authorization.

Kennedy was joined by Centers for Medicare & Medicaid Services Administrator Mehmet Oz as part of a roundtable discussion with insurers to discuss pledges made by the health insurance industry to streamline and reform the prior authorization process for Medicare Advantage, Medicaid Managed Care and Affordable Care Act Health Insurance Marketplace plans which account for most insured Americans.

The HHS Secretary commented on how when he joined the presidential transition team, he was told that the single most important thing he could do to improve the experience of patients across the nation was to “end the scourge of pre-authorization.”

Of course, the unsurers will argue that pre-authorization is necessary because those greedy doctors are recommending that surgery, MRI scan, specialty consultation, or physical therapy merely out of greed.

Steve Parker, M.D.