Kerin O’Dea (School of Population Health, U. of South Australia) performed one of the first clinical studies utilizing the paleo diet for treatment of type 2 diabetes. I discuss it in my Paleobetic Diet book and here.
O’Dea recently wrote:
“The most important lesson that can be drawn from this study is that metabolic control in type 2 diabetes can be greatly improved with healthy lifestyle interventions. The diet in the 1982 study was rich in very lean meat from wild animals: its high protein content aided satiety despite low energy intake [1,200 cal/day]. The carbohydrate was mostly high fibre and slowly digested. The fat content was low, but relatively rich in long chain highly polyunsaturated fats (omega-3 and omega-6). Recent research has demonstrated that ectopic fat is a driver of both defects of type 2 diabetes: insulin resistance when in the liver, and impaired insulin secretion when in the pancreas. Both are potentially reversible by healthy diets instituted early in the disease process. However, current population trends to increased obeisty are driven by the powerful transnational food industry. Preventive interventions will therefor be very challenging.”
Source: Pathology (2016), 48(S1), Abstract Supplement