Category Archives: Uncategorized

Is Schizophrenia an Autoimmune Disorder?

Dr. Emily Deans reviews the evidence at her blog.  Here’s the conventional explanation of schizophrenia from UpToDate.com:

“Although the pathogenesis [cause] of the disorder is unknown, it is almost certain that schizophrenia represents a syndrome comprised of multiple diseases that present with similar signs and symptoms. This heterogeneity complicates the elucidation of the etiological and pathophysiological factors that underlie the group of disorders. Schizophrenia appears to be a uniquely human condition, which limits the utility of animal models. There is little doubt that schizophrenia proceeds from a complex interaction between genes and the environment, but even the attempt to differentiate genetic from environment risk factors may be artificial, since environmental factors can influence gene expression just as a person’s genetic make-up can influence response to environmental stressors.”

Should Our Dietary Fats Be More Saturated Or Unsaturated?

The jury’s still out, but the editors at The Evolution and Medicine Review discuss dietary fat effects on gut microbiota and systemic inflammation.  The authors tend to favor unsaturated fats at this point.

Who Is Silverlobster?

My 14-year-old son is a budding artist.  His work is viewable and for sale at DeviantArt.  You can order prints of various sizes and quality, along with his art on cups and refrigerator magnets.  Thanks for taking a look.  Paul will get a kick out of the bump in page views whether you buy or not!

Some samples:

Wink!

Deadmau5 copy

Soaring eagle

Impressionist snake

REEEAOGH

QOTD: Adam Smith on Economic Self-Interest

“It is not from the benevolence of the butcher, the brewer, or the baker that we expect our dinner, but from their regard to their own interest.”

—Adam Smith, author of The Wealth of Nations

Paleo Diet is the Most Sought After

According to Janet Helm, RD.

Stephan Guyenet on “The Potato Diet”

Dr. Guyenet has a recent post on The Potato Diet.  It caught my eye since I include potatoes in my version of the paleo diet.  He starts thusly:

In 2010, I wrote a series of blog posts on the health properties of potatoes.  The evidence showed that potatoes are non-toxic, filling per calorie, remarkably nutritious, and can be eaten as almost the sole source of nutrition for extended periods of time (though I’m not recommending this).

Follow all of

Rosemary Chicken (garnished with pico de gallo) and Rosemary Potatoes

Rosemary Chicken (garnished with pico de gallo) and Rosemary Potatoes

Dr. Guyenet’s links and you’re sure to learn something new about potatoes.

-Steve

Could Acellular Carbohydrates Be the Cause of Obesity?

Ivor Goodbody in a recent tweet reminded me of an interesting nutrition science article.  Ian Spreadbury hypothesizes that carbohydrate density of modern foods may be the cause of obesity.  Refined sugars and grains—types of acellular carbohydrates—are  particularly bad offenders.

Harvesting acellular carbs

These acellular carbs may alter our gut microorganisms, leading to systemic inflammation and leptin resistance, etc.  Our Paleolithic ancestors had little access to acellular carbohydrates.

Read more about it in “Comparison with ancestral diets suggests dense acellular carbohydrates promote an inflammatory microbiota, and may be the primary dietary cause of leptin resistance and obesity,” in Diabetes, Metabolic Syndrome and Obesity: Targets and Therapy, 2012, vol. 5, pp. 175-189.

To reverse our modern obesity epidemic, we need better understanding of the underlying pathophysiology.

—Steve

PS:  For Spreadbury’s formal definition of acellular carbohydrates, see my long comment below.

Artificial Sweeteners and the Paleoista

Did you know babies under one year of age shouldn’t be given honey?  I saw that warning on a honey container recently and didn’t know why.  Honey may contain bacterial spores that cause botulism in the wee ones.

A pinch of salt helps reduce bitterness in coffee

Paleo diet aficionados can satisfy a sweet tooth with honey or fruit.  Unfortunately for people with diabetes, those items can spike blood sugars too high.  Honey, for instance, has 17 grams of carbohydrate in one tablespoon (15 ml), which is more carb than in a tablespoon of white granulated table sugar.

Most diabetics eating paleo-style will need some limit on consumption of honey and fruit.  Or they could take more diabetes drugs to control blood glucose elevations.  Again, unfortunately, we don’t know the long-term health effects of most of our diabetes drugs.

How about getting a sweet fix with artificial sweeteners?  Paleo purists would say “fuggedaboudit.”  In theory, that’s fine.  But many paleo followers with diabetes won’t forget about it.  They’ll use artificial sweeteners, aka sugar substitutes.

If you’re gonna use ’em, think about stevia.  It’s derived from a natural source, the leaves of a plant in South America.  Admittedly, our forebears in eastern Africa wouldn’t have had access to it 50,000 years ago.  After the plant has been processed, it’s certainly a highly refined product going against the grain of the paleo movement.  Furthermore, one of the stevia market leaders in U.S. (Truvia) is mixed with erythritol.  To help you feel better about the erythritol (a sugar alcohol), note that it is found naturally in some fruits.  Another stevia commercial product in the U.S. is Pure Via.

Dietitian Brenna at her Eating Simple blog reviewed sugar impostors in January, 2012.  She favored stevia over the others, at least for non-diabetics who were tempted.  Brenna also linked to a Mayo Clinic review of artificial sweeteners.

Note that sugar alcohols like erythritol have the potential to raise blood sugar levels.  They shouldn’t raise it as much as table sugar, however.  With regard to sugar alcohols, Dr. Richard K. Bernstein urges caution, if not total avoidance.  Use your meter to see how they effect you.

If you’re in the habit of using one or two teaspoons of honey to sweeten tea or coffee, you’re blood sugar levels should be more stable and manageable if you use stevia instead.  Dr. Bernstein gives the green light to stevia powder or liquid, along with saccharin tablets or liquid, aspartame tablets, and sucralose tablets, acesulfame-K, and neotame tablets.  Stevia is the only one close to “natural.”

Steve Parker, M.D.

Quote of the Day

“Frederick Douglass taught that literacy is the path from slavery to freedom. There are many kinds of slavery and many kinds of freedom, but reading is still the path.”

―Carl Sagan

Smoked Paprika on Eggs?

I’m glad eggs are on the paleo diet!  Love ’em.

Darya Pino suggests smoked paprika on fried eggs.  Not regular paprika, smoked.  Hope my local supermarket has it.  I got the fresh eggs—my chickens lay five a day, enough to share with the dogs now and then.

-Steve