Paleo Orthodontics: Dr. Mike Mew

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Orthodontist Mike Mew, BDS, MSc, did a presentation at Ancestral Health Symposium-2012 titled “Craniofacial Dystrophy—Modern Melting Faces.” Don’t let the title scare you off.

He says 30% of folks in Western populations have crooked teeth and/or malocclusion, and the mainstream orthodontic community doesn’t know why.  But they’ve got treatment for it!  Dr. Mew thinks he knows the cause and he shared it at the AHS-2012.  The  simple cure is “Teeth together.  Lips together.  Tongue on the roof of your mouth.”  And eat hard food.  Ideally in childhood before age 9.  Older people also benefit, he says.

I have no idea whether Dr. Mew is right or not.

I couldn’t get the video embedded here.  You can see it at The Paleo Periodical.

h/t PaleoPeriodical

Long-Term Maintenance for People With Diabetes

Contemplative Senior ManAs a diabetic or prediabetic trying to get and stay healthy, you need at least two other players on your healthcare team: a physician and a registered dietitian. Additionally, diabetes nurse educators can be quite helpful in teaching you to manage your condition. Other care team members may include physician assistants, nurse practitioners, pharmacists, and nutritionists.

Dietitians are particularly helpful consultants when diabetes is first diagnosed and periodically thereafter to answer food questions, check on compliance with diet recommendations, and to review new dietary guidelines. Unfortunately, a majority of dietitians still believe the out-dated idea that high-carbohydate eating is healthy for diabetics and others who have demonstrable difficulty processing carbs. Be sure the dietitian you choose supports a carbohydrate-restricted and paleo-friendly way of eating.

Many primary care physicians such as family physicians and internists are well-trained to co-manage diabetes with you. I chose the word “co-manage” carefully. It’s not like you have appendicitis and can turn over all management to a surgeon. With diabetes, you have to do more work than your physician. Your doctor will review your home glucose records, adjust medications, periodically examine you, and check blood work. You need a doctor who will support, or at least tolerate, your low-carb paleo way of eating.

An endocrinologist can be an invaluable team member, either as your main treating physician or as a consultant to your primary care physician. You should definitely see one if you are not close to the standard treatment goals after working with your primary care physician.

PERIODIC TESTS, TREATMENTS, AND GOALS

The American Diabetes Association (ADA) recommends the following items be done yearly (except as noted) in non-pregnant adults with type 2 diabetes. (Incidentally, I don’t necessarily agree with all ADA guidelines.) ADA guidelines with supporting documentation are available free on the Internet (search for “Standards of Medical Care in Diabetes—2013”):

  • Lipid profile (every two years if results are fine and stable)
  • Comprehensive foot exam
  • Screening test for distal symmetric polyneuropathy: pinprick, vibration, monofilament pressure sense
  • Serum creatinine and estimate of glomerular filtration rate
  • Test for albumin in the urine, such as measurement of albumin-to-creatinine ratio in a random spot urine specimen
  • Comprehensive eye exam by an ophthalmologist (if exam is normal, every two or three years is acceptable)
  • Hemoglobin A1c at least twice a year, but every three months if therapy has changed or glucose control is not at goal
  • Flu shots

Additionally, the ADA guidelines recommend:

  • Pneumococcal vaccination. “A one time re-vaccination is recommended for individuals >64 years of age previously immunized when they were <65 years of age if the vaccine was administered >5 years ago.” Also repeat the vaccination after five years for patients with nephrotic syndrome, chronic kidney disease, other immunocompromised states (poor ability to fight infection), or transplantation.
  • Weight loss for all overweight diabetics. “For weight loss, either low-carbohydrate [under 130 g/day], low-fat calorie-restricted, or Mediterranean diets may be effective in the short-term (up to two years).” For those on low-carb diets, monitor lipids, kidney function, and protein consumption, and adjust diabetic drugs as needed. “The optimal macronutrient composition of weight loss diets has not been established.” (Macronutrients are carbohydrates, proteins, and fats.)
  • Limit alcohol to one (women) or two (men) drinks a day.
  • Limit saturated fat to less than seven percent of calories.
  • During initial diabetic exam, screen for peripheral arterial disease (poor circulation). Strongly consider calculation of the ankle-brachial index for those over 50 years of age; consider it for younger patients if they have risk factors for poor circulation.
  • In the early stages of diabetic chronic kidney disease, reduce protein intake to 0.8-1.0 grams per kilogram of body weight. In later stages, reduce to 0.8 grams per kilogram of body weight.
  • Those at risk for diabetes, including prediabetics, should aim for a) moderate weight loss (about seven percent of body weight) if overweight, through low-fat/reduced-calorie eating, b) exercise: 150 minutes per week of moderate-intensity aerobic activity.

Some of my dietary recommendations you’ve read on my blogs conflict with ADA guidelines. The experts assembled by the ADA to compose guidelines were well-intentioned, intelligent, and hard-working. The guidelines are supported by over 350 scientific journal references. I greatly appreciate the expert panel’s work. We’ve simply reached some different conclusions. By the same token, I’m sure the expert panel didn’t have unanimous agreement on all the final recommendations. I invite you to review the dietary guidelines yourself, discuss with your personal physician, then decide where you stand.

GENERAL TREATMENT GOALS

The ADA suggests general therapeutic goals for adult non-pregnant type 2 diabetics:

  • Fasting blood glucoses: 70 to 130 mg/dl (3.9 to 7.2 mmol/l)
  • Peak glucoses one to two hours after start of meals: under 180 mg/dl (10 mmol/l)
  • Hemoglobin A1C: under 7%
  • Blood pressure: under 130/80 mmHg
  • LDL cholesterol: under 100 mg/dl (2.6 mmol/l). (In established cardiovascular disease: <70 mg/dl or 1.8 mmol/l.)
  • HDL cholesterol: over 40 mg/dl (1.0 mmol/l) for men and over 50 mg/dl (1.3 mmol/l) for women
  • Triglycerides: under 150 mg/dl (1.7 mmol/l)

The American Association of Clinical Endocrinologists (AACE) in 2007 proposed somewhat “tighter” goals:

  • Fasting blood glucoses: under 110 mg/dl (6.11 mmol/l)
  • Peak glucoses 2 hours after start of meals: under 140 mg/dl (7.78 mmol/l)
  • Hemoglobin A1C: under 6.5%

The ADA reminds clinicians, and I’m sure the AACE guys agree, that diabetes control goals should be individualized, based on age and life expectancy of the patient, duration of diabetes, other diseases that are present, individual patient preferences, and whether the patient is able to easily recognize and deal with hypoglycemia. I agree completely. For instance, there’s not much reason to aim for blood sugars of 100 mg/dl (5.56 mmol/l) in a 79-year-old expected to die of lung cancer in four months. The goal is comfort and symptom relief, even if sugars are 220 mg/dl (12.2 mmol/l).

Admittedly, the aforementioned goals are difficult for many diabetics to achieve, but they are worth your effort in terms of avoiding long-term complications of diabetes. You will need to see your doctor every three to six months, and more often if your glucoses are not well-controlled or you have other medical issues.

Steve Parker, M.D.

Paleo Diet Advocates Fear Modernity

…according to David Gorski at Science-Based Medicine.

Gee, I hadn’t noticed that fear.  Maybe it’s subconscious.

Dr. Gorski makes some good points along with others I disagree with.  I expect the commentators at SBM will address many of the controversial points.  They’re a smart readership.

One uncommon observation of his is that the “complementary and alternative medicine” believers tend to embrace the paleo diet and lifestyle.  I’ve noticed that also.  To the extent that the CAM folks are often unscientific or anti-scientific, those of us examining the paleo diet from a scientific viewpoint have to be wary of “guilt by association.”

A major point that Dr. Gorski didn’t address is that living hunter-gatherers studied over the last century or two don’t have nearly as much cardiovascular disease and death as modern Western societies.  That’s a common meme in the paleosphere, started by the prominent paleo book authors.  (I’ve not reviewed the original sources.)  I’m talking about lower rates of heart attacks, strokes, hypertension, peripheral arterial disease, and premature death.  Note that the mere presence of atherosclerosis may not correlate with these hard clinical endpoints.

My Critique of the Joslin Critique of the Paleo Diet

paleo diet, Paleolithic diet, hunter-gatherer diet

Huaorani hunter in Ecuador

The Joslin Diabetes Blog yesterday reviewed the paleo diet as applied to both diabetes and the general public.  They weren’t very favorably impressed with it.  But in view of Joslin’s great reputation, we need to give serious consideration to their ideas.  (I don’t know who wrote the review other than “Joslin Communications.”)

These are the main criticisms:

  • diets omitting grains and dairy are deficient in calcium and possibly B vitamins
  • you could eat too much total and saturated fat, leading to insulin resistance (whether type 1 or 2 diabetes) and heart disease
  • it’s not very practical, partly because it goes against the grain of modern Western cultures
  • it may be expensive (citing the cost of meat, and I’d mention fresh fruit and vegetables, too)

Their conclusion:

There are certainly better diets out there, but if you are going to follow this one, do yourself a favor, take a calcium supplement and meet with a registered dietitian who is also a certified diabetes educator  to make sure it is nutritionally complete, isn’t raising your lipids and doesn’t cause you any low blood glucose incidences.

Expense and Practicality

These take a back seat to the health issues in my view.  Diabetes itself is expensive and impractical.  Expense and practicality are highly variable, idiosyncratic matters to be pondered and decided by the individual.  If there are real health benefits to the paleo diet, many folks will find work-arounds for any expense and impracticality.  If the paleo diet  allows use of fewer drugs and helps avoid medical complications, you save money in health care costs that you can put into food.  Not to mention quality of life issues (but I just did).

Calcium and B Vitamin Deficiencies

This is the first I’ve heard of possible B vitamin deficiencies on the paleo diet.  Perhaps I’m not as well-read as I thought.  I’ll keep my eyes open for confirmation.

The potential calcium deficiency, I’ve heard of before.  I’m still open-minded on it.  I am starting to wonder if we need as much dietary calcium as the experts tell us.  The main question is whether inadequate calcium intake causes osteoporosis, the bone-thinning condition linked to broken hips and wrists in old ladies.  This is a major problem for Western societies.  Nature hasn’t exerted much selection pressure against osteoporosis because we don’t see most of the fractures until after age 70.  I wouldn’t be surprised if we eventually find that life-long exercise and adequate vitamin D levels are much more important that calcium consumption.

With regards to calcium supplementation, you’ll find several recent scientific references questioning it.  For example, see this, and this, and this, and this, and this.  If you bother to click through and read the articles, you may well conclude there’s no good evidence for calcium supplementation for the general population.  If you’re not going to supplement, would high intake from foods be even more important?  Maybe so, maybe not.  I’m don’t know.

If you check, most of the professional osteoporosis organizations are going to recommend calcium supplements for postmenopausal women, unless dietary calcium intake is fairly high.

If I were a women wanting to avoid osteoporosis, I’d do regular life-long exercise that stressed my bones (weight-bearing and resistance training) and be sure I had adequate vitamin D levels.  And men, you’re not immune to osteoporosis, just less likely to suffer from it.

Insulin Resistance

Insulin resistance from a relatively high-fat diet is theoretically possible.  In reality, it’s not common.  I’ve read plenty of low-carb high-fat diet research reports in people with type 2 diabetes.  Insulin levels and blood glucose levels go down, on average.  That’s not what you’d see with new insulin resistance.  One caveat, however, is that these are nearly all short-term studies, 6-12 weeks long.

If you have diabetes and develop insulin resistance on a high-fat diet, you will see higher blood sugar levels and the need for higher insulin drug doses.  Watch for that if you try the paleo diet.

Are High Total and Saturated Fat Bad?

Regarding relatively high consumption of total and saturated fat as a cause of heart or other vascular disease: I don’t believe that any more.  Click to see why.  If you worry about that issue, choose meats that are leaner (lower in fat) and eat smaller portions.  You could also look at your protein foods—beef, chicken, fish, eggs, offal, etc.—and choose items lower in total and saturated fat.  Consult a dietitian or online resource.  Protein deficiency is rarely, if ever, a problem on paleo diets.

In Conclusion

I think the paleo diet has more healthful potential than realized by the Joslin blogger(s).  I’m sure they’d agree we need more clinical studies of it, involving both type 1 and 2 diabetics.  I appreciate the “heads up” regarding potential vitamin B deficiencies.  My sense is that the Joslin folks are willing to reassess their position based on scientific studies.

I bet some of our paleo-friendly registered dietitians have addressed the potential adverse health issues of the paleo diet.  Try Amy KubalFranziska Spritzler (more low-carb than paleo) or Aglaée Jacob.  I assume the leading paleo diet book authors have done it also.

If you’re worried about adverse blood lipid changes on the paleo diet, get them tested before you start, then after two months of dieting.

Steve Parker, M.D.

PS: The paleo diet is also referred to as the Stone Age diet, caveman diet, Paleolithic diet, hunter-gatherer diet, and ancestral diet.

Is the Overbite We Take for Granted Only a Few Centuries Old?

The New Yorker has a review of Bee Wilson’s book, Consider the Fork: A History of How We Cook and Eat.  The book touches on everything from daggers to toothpicks to chopsticks.  It’s about the evolution of cutlery.  Even if you don’t have the time or interest for the book, the review by Jane Kramer is interesting.  An excerpt:

This new cutlery [forks and various knives] transformed the way people ate. By the late eighteenth century in Europe, people were slicing their food into bite-size morsels and carrying them to their mouths with forks—those formerly weird things, Wilson calls them. And they hardly needed to chew such tiny pieces, which in most cases were already softened by pounding, overcooking, or long, gentle braisings. At the same time, the modern overbite began to appear prominently in upper-class Western European jaws. Do not confuse this with the seriously inconvenient condition known to the world as buck teeth (without which we would have no orthodontists, and no mortified adolescents with mouthfuls of rubber bands and wire braces). Wilson’s modern overbite refers to “the way our top layer of incisors hangs over the bottom layer, like a lid on a box,” as she nicely puts it, and is “the ideal human occlusion” for the way we now eat. Why this happened and how long it took to happen is open to some debate, but it’s clear that until it happened most humans had the bite of other primates—“where the top incisors clash against the bottom ones, like a guillotine blade.”

Read more: http://www.newyorker.com/arts/critics/books/2013/03/18/130318crbo_books_kramer#ixzz2NVA79mWJ

Bee Wilson is a food writer and historian, not an anthropologist or orthodontist.

Matthew Yglesias Says “Paleo Diet Is Nonsense Science”

Here’s his brief article at Slate.  Mr. Yglesias was apparently influenced by Marlene Zuk.

Well, now that that’s settled, I can shut down this blog and start another hobby.

https://twitter.com/johndurant/status/311369697658564608

Man’s Best Friend For How Long?

Dogs May Have Been Domesticated 33,000 Years Ago according to an article at Yahoo!News.  The DNA in the old skull found in Siberia was a closer match to dogs than to wolves.  Apart from the DNA evidence, the skull appeared more similar to a dog’s than an wolf’s.  Earlier evidence suggested dogs were first domesticated in the Middle East or East Asia.

Here’s the report in PLOS One.

Sarah Ballantyne, Ph.D., Recommends Against Stevia

See her pertinent post, an excerpt from her book.

I’m not convinced, but readily admit I’ve not studied the issue in detail.  I’ve got a raging sweet tooth, so maybe I’m biased.  Is Dr. Ballantyne’s proscription of stevia another over-application of the Precautionary Principle?

 

h/t Aglaée Jacobs, RD (twitter: @aglaee_paleoRD)

Fruit May Not Sabotage Control of Type 2 Diabetes

…according to an article in Nutrition Journal.  Fruit is a prominent component of the paleo diet.  It can be good for us, containing phytonutrients, fiber, etc.  But fruit has the potential to increase blood sugars, too, which may be harmful over the long run.  So whadda you do?

Researchers took newly diagnosed type 2 diabetics and split them into two groups. One group was told to eat at least two pieces of fruit daily, the other was told to eat no more than two pieces.

The researchers conclusions: 

A recommendation to reduce fruit intake as part of standard medical nutrition therapy in overweight patients with newly diagnosed type 2 diabetes resulted in eating less fruit. It had however no effect on HbA1c, weight loss or waist circumference. We recommend that the intake of fruit should not be restricted in patients with type 2 diabetes.

Read the full research report.

 

PS: I haven’t read the full report yet.

More Ancient Cultures Found With Atherosclerosis

…according to a report by Larry Husten at CardioBrief.  Mummies in the study were from Egypt (the majority), the American southwest, Peru, and Alaska.  Atherosclerosis was detected by CT scanning.  The Associated Press reports the mummies were between 100 and 6,000 years old.  At least one of the four cultures was described as hunter-gatherer (Anangan).

MedPageToday also covered the story.

Mr. Husten quotes the investigators:

Our findings greatly increase the number of ancient people known to have atherosclerosis and show for the first time that the disease was common in several ancient cultures with varying lifestyles, diets, and genetics, across a wide geographical distance and over a very long span of human history. These findings suggest that our understanding of the causative factors of atherosclerosis is incomplete, and that atherosclerosis could be inherent to the process of human ageing.

All of the studied ancient peoples probably had significant exposure to smoke from fires, which could cause atherosclerosis.

Perhaps atherosclerosis is just part of being human.  I’ve always told my patients they’ll get atherosclerosis if they live long enough.

Since atherosclerosis causes heart attacks and strokes and death, we like to think we can prevent it or modify it’s course through diet and other lifestyle modifications.  That’s true…to an uncertain extent.