Tag Archives: paleo diet

Prediabetes and Diabetes on the March in U.S. Adolescents

The June, 2012, issue of Pediatrics has an article stating that the incidence of diabetes and prediabetes in U.S. adolescents increased from 9% in 1999 to 23% in 2008.  The finding is based on the NHANES survey of 12 to 19-year-olds, which included a single fasting blood sugar determination.

The investigators offered no solution to the problem.  I’m no pediatrician, but my educated guess is that the following measures would help prevent adolescent type 2 diabetes and prediabetes:

  • more exercise
  • eat less refined starches and sugar
  • maintain body weight in the healthy range
I’m sure many of the adolescent type 2 diabetics and prediabetics are overweight or obese.  A 2010 study out of Colorado found a low-carbohydrate, high-protein diet safe and effective for adolescents.  Fortunately, the decades-long ascent of the adolescent obesity rate in the U.S. seems to have peaked for now.
The paleo diet would restrict consumption of concentrated sugars and refined starches, but it’s hard to get adolescents to skip those items.

Steve Parker, M.D.

PS: I scanned the article quickly and don’t remember if the researchers broke down the diabetes cases by type 1 and type 2.  I’d be shocked if type 1 diabetes rose this much over the last decade.

Does the Paleo Diet Cause Kidney Stones?

MedPage Today in May, 2012, reported a substantial increase (70%) in the prevalence of kidney stones in the U.S. over the last two decades. Stone prevalence rose from 5.2% to 8.8% of the population.  Prevalence was based on the periodic National Health and Nutrition Examination Survey, which asked participants, “Have you ever had kidney stones?”

Starting a hundred-yard DASH

Stone prevalence began rising even earlier.  Again according to the third NHANES, prevalence increased from 3.8 percent in the period 1976 to 1980 to 5.2 percent in the years 1988 to 1994.

Older studies estimated that one in 10 men and one of every 20 women will have at least one painful stone by the age of 70.

What are kidney stones make of?  

Three out of four patients with kidney stones form calcium stones, most of which are composed primarily of calcium oxalate or, less often, calcium phosphate.  Pure uric acid stones are less than 10 percent of all stones.

Why the increased stone prevalence?  Does diet count?

Unfortunately, the article doesn’t offer any reasons or even speculation as to why kidney stones are more prevalent.  Kidney stones have a genetic component, but our genes have changed very little over just two decades.  I have to wonder if diet plays a role.

UpToDate.com reviewed diet as a risk factor for kidney stones.  Some quotes:

There are several dietary factors that may play an important role in many patients: fluid, calcium, oxalate, potassium, sodium, animal protein, phytate, sucrose, fructose, and vitamin C intake. Lower intake of fluid, calcium, potassium, and phytate and higher intake of sodium, animal protein, sucrose, fructose, and vitamin C are associated with an increased risk for calcium stone formation. The type of beverage may also influence the risk. The effect of calcium intake is paradoxical, with a decreased risk with increased dietary calcium and an increased or no change in risk with calcium supplements.

The combination of dietary factors may also have a significant impact upon stone risk. As an example, the Dietary Approaches to Stop Hypertension (DASH) diet is high in fruits and vegetables, moderate in low-fat dairy products, and low in animal protein. Based upon an analysis of three large cohorts, adherence to a DASH-style diet lowered the risk for kidney stones among men, older women, younger women, high body mass index (BMI) individuals, and low BMI individuals. Thus, the DASH diet is a reasonable option in the attempt to reduce the risk of stone recurrence.

Higher sucrose [table sugar] intake is associated with an increased risk of stone formation in younger and older women.
The statements above link both low sucrose and high sucrose consumption to kidney stones, so I’m going to ignore sucrose.  The paleo diet, of course, does’t supply much sucrose.
I thought I read somewhere that the paleo diet is potentially deficient in calcium, but I can’t find the reference.  Dr. Cordain at his website suggests that the formal recommended dietary allowance is set too high in any case.  If the diet’s low in calcium, it could predispose to stones. On the other hand, most paleo diet versions are low in sodium and rich in potassium, which may protect against stones.
In Cordain’s 2002 Paleo Diet book, he writes:
In virtually every dietary permutation [of the paleo diet] the levels of vitamins and minerals exceed governmental recommended RDAs.
So does the paleo diet cause kidney stones?  Sorry, but I don’t know.  I tend to doubt it.  I’m not aware of any scientific studies comparing the prevalence of kidney stones in those eating paleo-style with an otherwise similar population.
What about stone prevalence in modern hunter-gatherer cultures?  I bet those data exist, but searching “urolithiasis AND hunter-gatherer” got me nothing at PubMed.  Comparing those cultures with modern Western ones is probably a fool’s errand anyway: too many other uncontrolled variables besides diet.
Standard advice to prevent initial and recurrent kidney stones is to avoid low urine output.  Do that by drinking plenty of fluid.
Although I pay $400 a year for access to UpToDate, they offer free public access to some of the website.  Here’s the UpToDate poop sheet on kidney stones.
Extra credit:  Medical conditions that predispose to kidney stones include primary hyperparathyroidism, obesity, gout, diabetes, and medullary sponge kidney.
For SEO: The paleo diet is also called Stone Age, Old Stone Age, Paleolithic, caveman, and hunter-gatherer, and ancestral diet.

I Found a Paleo-Friendly Physician

Dr. Ernie Garcia is an internist in Louisiana treating some of his patients—particularly those with high blood pressure and diabetes—with the paleolithic lifestyle.  (Mostly  paleo diet, or other aspects of paleo lifestyle, too?)

Read more at PaleolithicMD.

Steve Parker, M.D.

Nephrologist and Type 1 Diabetic Keith Runyan Tried the Paleo Diet

Jimmy posted a recent interview with type 1 diabetic Dr. Keith R. Runyan, who is a nephrologist and internist.

Dr. Runyan is training for the Great Floridian Triathlon this coming October so he naturally has a great interest in high level athleticism as it intersects with diabetes.  He fuels his workouts with dietary fats and proteins rather than the standard carbohydrates.

Dr. Runyan’s current carb consumption level didn’t come up specifically in the interview, but his website indicates he’s on a ketogenic diet heavily influenced by Dr. Richard Bernstein.  I figure he’s eating under 50 grams of digestible carbohydrate daily.  He also tried Loren Cordain’s paleo diet; my sense is that it didn’t help much with his diabetes, but perhaps some.  My sense is that he incorporates at least a few paleo features into his current eating plan.

People with type 2 diabetes can probably tolerate a higher level of carbohydrates, compared to type 1’s, generally speaking.  This didn’t come up in the podcast interview.

Overall, the interview strongly supports carbohydrate-restricted eating for folks with diabetes.  Definitely worth a listen for anyone with diabetes who’s not sold on a very-low-carb diet.  If you’re sitting on the fence, at least check out Dr. Runyan’s “About Me” page.

Steve Parker, M.D.

Triathlon: run, swim, bike

Can A Christian Be A Paleo Advocate?

If you’re squeamish about discussions of religion and God, read no further! What follows is controversial and much of it not subject to scientific investigation.

In case you’re wondering, I’m a Christian.  This simply means I believe I was given life by God, that His son Jesus became a man and died for my sins, and that I will have everlasting life in heaven for believing on this.  I strive to live the way God would want me to live, as written in the Holy Bible.  I was brought up in the Catholic faith, even attending parochial school in grades 1-8, but I’m Protestant now.  I went through an agnostic period between the ages of 19 to about 38—I’m glad I made it through that alive!

I’ve been learning more about paleo eating over the last year since it overlaps a fair amount with low-carb eating. (Paleo-style eating is also referred to as ancestral, Old Stone Age, hunter-gatherer, or the caveman diet.) The Paleolithic Era covers about 1.5 to 2 million years of human evolution, admitting that there probably hasn’t been much genetic change over the last 50,000 years (debatable). The cornerstone of paleo eating is that we should eat the things we are evolutionarily adapted to eat. We’ll be healthier that way. We didn’t have corn chips, soda pop, and candy bars 20,000 years ago, so we shouldn’t be eating them now.

Sounds reasonable, doesn’t it? Various species of animals thrive on certain foods and not others. My horses eat three meals a day – all hay; you and I couldn’t survive on that.

I have a college degree in Zoology, so I was thoroughly indoctrinated in Charles Darwin‘s evolutionary theory, at least the version current in the mid-1970s. Darwin’s theory requires no God, or didn’t include a role for God or gods. How Darwinians answer the question of Creation, I don’t know.

Many proponents of evolutionary theory seem to be atheist or agnostic. Natural selection determines who lives or dies, not the hand of God. Some brands of Christianity, but not all, reject the idea of human evolution in its entirety. They believe God created us just as we are about 6,000 years ago. So can a Christian be a paleo diet advocate?

(I don’t know where Judaism, Islam, and other major religions stand on evolution.)

Human evolution is central to paleo diet theory. A religious person may reject the idea of human evolution; can he nevertheless participate in the modern “paleo community”?

I believe God made us and the universe. There’s no proof – it’s a matter of faith. I don’t know if He made us 6,000 years ago or two million.  The bulk of the science speaks clearly against 6,000 years ago.

Our bodies are made to thrive on certain foods and not others.  That’s true for all animals.  If you find an injured bird in your yard and hope to nurse it back to health,  you better find out what it eats naturally and provide it, or you’ll fail.  The range of foods humans can thrive on is pretty broad. Whether the optimal way of eating is determined by godless evolutionary processes or by the intelligent design of a Creator doesn’t matter so much if you’re looking at it from a purely nutritional viewpoint.

From an “everlasting life” viewpoint, it matters.  Big time.

The paleo guys might be right about the best way to eat. Science continues to accumulate evidence one way or the other.

Christianity and paleo diet theory are not mutually exclusive. A Christian can ignore the possiblity of a million years of evolution, believing instead that God made our bodies in such a way that we’d be healthier eating certain foods and not others. Those foods may be the components of the paleo diet, whatever that is.

Steve Parker, M.D.

Further reading:

Carl Drews has written extensively on Christianity and Evolution, including his essay on Theistic Evolution.

Phil Porvaznik’s article on theistic evolution and the Roman Catholic Church.

Wikipedia: Catholic Church and Evolution.

Can a Christian follow a paleo low-carb diet? at Jimmy Moore’s Livin’ La Vida Low-Carb blog.

A few questions for the atheists.  Where did the universe come from?  Was it created? By whom or what?  What if God exists, and he made us for a reason and wants us to live a certain way?

Consider this excerpt from Walter Isaacson’s book, “Einstein: His Life and Universe”:

One evening in Berlin, [Albert] Einstein and his wife were at a dinner party when a guest expressed a belief in astrology. Einstein ridiculed the notion as pure superstition. Another guest stepped in and similarly disparaged religion. Belief in God, he insisted, was likewise a superstition.

At this point the host tried to silence him by invoking the fact that even Einstein harbored religious beliefs.

“It isn’t possible!” the skeptical guest said, turning to ask Einstein if he was, in fact, religious.

“Yes, you can call it that,” Einstein replied calmly. “Try and penetrate with our limited means the secrets of nature and you will find that, behind all the discernible laws and connections, there remains something subtle, intangible and inexplicable. Veneration for this force beyond anything we can comprehend is my religion. To that extent, I am, in fact, religious.”

Melanie Gores a Few Oxen

Australian Aborigine

Dietitian Melanie Thomassian at Dietriffic offers some iconoclastic ideas in her critique of the paleo diet (aka Paleolithic, Old Stone Age, caveman, or hunter-gatherer diet).  Some quotes:

I’ll be the first to admit the diet recommended by most mainstream nutritionists, dietitians, and doctors is pretty terrible, and believe it or not, I do understand why people look elsewhere for their dietary advice.

 

The philosophy and reasoning behind the whole Paleo diet, however, isn’t something I can reconcile myself to.

Melanie addresses legumes, dairy, grains, and the problem of determining prehistoric diets.

-Steve

Classic Australian Aborigine Study on Return to Ancestral Diet and Lifestyle

Did you know kangaroo is edible?

The scientific article I review today is often cited by those who favor a Paleolithic diet for diabetics.  Cordain and Stefanson have written about it, for example.

Background

Urbanized Australian Aboriginal communities have a high prevalence of type 2 diabetes.   Kerin O’Dea writes:

The change from an urban to a traditional lifestyle involves several factors that directly affect insulin sensitivity: increased physical activity, reduced energy intake and weight loss, and changes in the overall dietary composition.  All of these factors improve insulin sensitivity and should, therefore, be of benefit to the insulin-resistant diabetic.

Methods

Ten urban type 2 diabetic and four nondiabetic full-blood Aborigines agreed to revert to their traditional lifestyle as hunter-gatherers in an isolated region of Australia for seven weeks.  Average age was 53.  Half of them were moderate to heavy alcohol drinkers.  Average diabetic weight was 82 kg (180 lb); nondiabetics averaged 77 kg (169 lb).  There were equal numbers of men and omen.  None of the diabetics was on insulin, and only one was on an oral diabetic drug (a sulfonylurea). 

Ayers Rock, Uluru National Park, Australia

The study was carried out at Pantijan, the traditional land of these Aborigines.  It’s a day-and-a-half drive in a four-wheel vehicle from Derby.  At least it was in 1984.

For seven weeks, the participants ate only what they hunted or collected.  Diet composition was dependent on whether they were travelling to the homeland (1.5 weeks), at the coastal location (2 weeks), or inland on the river (3.5 weeks). Protein sources were mainly beef, kangaroo, fish, birds, crocodiles, and turtles.  Carboydrate content ranged from under 5% to 33%.  Protein content varied from 50 to 80%.  Fat was 13 to 40%.  So, very high protein and low-carb.  Carb sources were yams, honey, and figs.  Yams were the predominant carb source.  They also eat yabbies (shrimp or crayfish (“crawdads” in Oklahoma)).  Average energy intake was a very low 1,200 calories a day. 

The author implies this was the traditional Aboriginal diet.

What did they eat back home in the city? 

The main dietary components were flour, sugar, rice, carbonated drinks, alcoholic drinks (beer and port), powdered milk, cheap fatty meat, potatoes, onions, and variable contributions of other fresh fruit and vegetables. 

O’Dea estimates a macronutrient breakdown of 50% carb, 40% fat, and 10% protein (similar to the Standard American Diet, then).

What Did O’Dea Find Out?

Everyone lost weight, a group average of 8 kg (18 lb) over the seven weeks.

Fasting blood sugars fell in the diabetics from 11.6 mmol/l to 6.6 mmol/l (209 to 119 mg/dl).  After-meal blood sugars also fell dramatically.

Fasting insulin levels fell from 23 to 12 mU/l.

Fasting triglycerides fell drastically. 

HDL cholesterol fell significantly, whereas LDL cholesterol tended to rise.

So What?

How often do you see a scientific article with just one author?  Rarely, these days.

The investigator wrote that, “Under the conditions of the study it is difficult to separate out effects of dietary composition, low energy intake, and weight loss.”

O’Dea estimates that experimental activity levels were probably higher than in the urban setting, but not dramatically more so.  (He was with the participants throughout the experiment.)

The main carbohydrate sources in this ancestral diet were yams, honey, and figs.  Modern Australian honey is probably similar to the honey of 100,000 years ago.  But what about yams and figs? 

These folks had to have been eating twice as many calories, at least, back in their urban environment.  O’Dea didn’t comment on how well the participants tolerated calorie restriction.  Did they complain?  Did they eat to satiety?  They had no access to food other than what they could hunt and gather.  Was food in short supply?  It’s not documented.  You’d think O’Dea would mention these issues if they were a problem. 

This particular ancestral diet was extremely high in protein: 50–80% of calories.  (Eaton and Konner suggest that an average ancestral diet provides only 25–30% of total calories from protein.  A typical modern high-protein diet derives about 30% of calories from protein, compared with 15–18% in the standard American diet.)  Protein helps combat hunger.  But halving caloric intake for seven weeks is extreme.  Don’t believe me?  Just try it.  This degree of caloric restriction by itself would tend to lower blood sugar levels and body weight in most humans, regardless of macronutrient ratios and ethnicity.

I know nothing about Australian Aborigines as an ethnic and genetic group.  Is their diabetes similar to European diabetes?  Pima Indian diabetes?   

O’Dea never called the study diet Paleolithic, because it wasn’t. It was a modern hunter-gatherer diet eaten by rural, isolated Australian Aboriginal communities.

This calorie-restricted, very-high-protein, natural diet was very effective for weight loss and blood sugar control in this tiny, seven-week study on a specific ethnic population.  I bet the caloric restriction was the most effective component of the lifestyle change.  Restriction of refined sugars and starches also helped. 

This ancestral diet was beneficial for a few Australian Aborigines.  Are the lessons widely applicable?  Not yet.  As they say, “further studies are needed.”  You can’t just cite this study to say that paleo diets are healthy for diabetics.

It does jibe with plenty of other research that shows severe calorie restriction leads to weight loss and lower blood sugar levels.

Steve Parker, M.D.

Reference: O’Dea, Kerin.  Marked improvement in carbohydrate and lipid metabolism in diabetic Australian Aborigines after temporary reversion to traditional lifestyle.  Diabetes, 33 (1984): 596-603.

Frustration

I just realized I started this blog six months ago with the idea that I’d “…share my investigation into whether the paleo diet and lifestyle are potentially therapeutic for people with diabetes.”

I’m frustrated that I haven’t made more progress.

Only a few clinical studies have looked at use of the paleo diet in diabetics.  And only type 2’s at that.  The Swedes (Steffan Lindeberg/Tommy Jonsson group) and Californians (Team Frassetto) own this field, at this point.

Loren Cordain is at Colorado State University.  Don’t they have a research department?

Are S. Boyd Eaton and Melvin Konner still in academia?

Namesake of the Cabbage Soup Diet

I found an article from 1984 looking at return of diabetic Australian aborigines to their traditional lifestyle.  I’ll report here after I analyze it.

Dr. Jay Wortman has done work with aboriginal peoples of Canada.  They have lots of diabetes, like the Pima in my neck of the woods.  I’ll look for his results.

If the paleo diet is ever going to be more than a fad, we need clinical studies that support it.  Shoot, even the cabbage soup diet has glowing anecdotal reports from individuals, but it hasn’t stood the test of time.

Am I missing any clinical studies?

Steve Parker, M.D.

PS: I still expect a flurry of paleo diet studies to be published in the next 5-10 years, involving several types of human participants (diabetics, overweight and obese, heart patients, hypertensives, etc.).  Then again, maybe I’m wrong.

PPS: Instead of “paleo diet,” you may prefer Old Stone Age diet, Stone Age diet, caveman diet, hunter-gatherere diet, Paleolithic diet, or Ancestral diet

Short-Term Effects of a Paleolithic Diet in Healthy Medical Students

Stockholm Palace

Swedish investigators at Karolinska Institutet found diminished weight, body mass index, blood pressure, and waist circumference in 14 healthy medical students eating a paleo diet for three weeks.

Published in 2008, this seems to be one of the seminal scientific studies of the paleo diet in modern Europeans.

Their version of the paleo diet:

  • Allowed ad lib: All fresh or frozen fruits, berries and vegetables except legumes, canned tomatoes w/o additives, fresh or frozen unsalted fish and seafood, fresh or frozen unsalted lean meats and minced meat, unsalted nuts (except peanuts – a  legume), fresh squeezed lemon or lime juice (as dressing), flaxseed or rapeseed oil (as dressing), coffee and tea (w/o sugar, milk, honey, or cream), all salt-free spices.
  • Allowed but with major restrictions: dried fruit, salted seafood, fat meat, potatoes (two medium-sized per day), honey, cured meats
  • Prohibited: all milk and dairy products, all grain products (including corn and rice), all legumes, canned food except tomatoes, candy, ice cream, soft drinks, juices, syrups, alcohol, sugar, and salt

What Did They Find After Three Weeks?

  • Average weight dropped from 65.2 kg (144 lb) to 62.9 (139 lb) 
  • Average body mass index fell from 22.2 to 21.4
  • Average waist circumference decreased from 74.3 cm (29.25″) to 72.6 cm (28.58″) 
  • Average systolic blood pressure fell from 110 to 104 mmHg
  • plasminogen activator inhibitor-1 decreased from 5.0 kIE/l to 2.8 kIE/l
  • All of these changes were statistically significant

The researchers looked at a number of other blood tests and didn’t find any significant differences. 

Five men and nine women completed the study.  Of the 20 who originally signed up, one could not fulfill the diet, three became ill (no details), two failed to show up.

So What?

That’s a remarkable weight loss over just three weeks for slender people eating ad lib.

The study authors concluded that these paleo diet-induced changes could reduce risk for cardiovascular disease.  They called for a larger study with a control group.  (If it’s been done, I haven’t found it yet.)

Sounds reasonable.

Steve Parker, M.D.

PS: You’d think they would have said more about the three participants who got sick, rather than leave us wondering if the diet made them ill.

Reference:  Österdahl, M; Kocturk, T; Koochek, A;Wändell, PE.  Effects of a short-term intervention with a paleolithic diet in healthy volunteers.  European Journal of Clinical Nutrition, 62 (2008): 682-685.

Random Thoughts On Paleo Eating For People With Diabetes

Not really pertinent, but I like buffalo

I was interviewed  yesterday by Amy Stockwell Mercer, author of Smart Woman’s Guide to Diabetes.  All I knew beforehand was that she was interested in my thoughts on the paleo diet as applied to diabetes.

In preparation, I collected some random thoughts and did a little research.

What’s the paleo diet?

Fresh, minimally processed food.  Meat (lean or not? supermarket vs yuppiefied?), poultry, eggs, fish, leafy greens and other vegetables, nuts, berries, fruit, and probably tubers.

Non-paleo: highly processed, grains, refined sugars, industrial plant/seed oils, legumes, milk, cheese, yogurt, salt, alcohol.

Is the paleo diet deficient in any nutrients?

A quick scan of Loren Cordain’s website found mention of possible calcium and vitamin D deficits.  Paleoistas will get vitamin D via sun exposure and fish (especially cold-water fatty fish).  Obtain calcium from broccoli, kale, sardines, almonds, collards.  (I wonder if the Recommended Dietary Allowance for calcium is set too high.)

What About Carbohydrates and Diabetes and the Paleo Diet?

Diabetes is a disorder of carbohydrate metabolism.  In a way, it’s an intolerance of carbohydrates.  In type 1 diabetes, there’s a total or near-total lack of insulin production on an autoimmune basis.  In type 2 diabetes, the body’s insulin just isn’t working adequately; insulin production can be high, normal or low.  In both cases, ingested carbohydrates can’t be processed in a normal healthy way, so they stack up in the bloodstream as high blood sugars.  If not addressed adequately, high blood glucose levels sooner or later will poison body tissues .  Sooner in type 1, later in type 2.  (Yes, this is a gross over-simplification.) 

Gluten-rich Neolithic food

If you’re intolerant of lactose or gluten, you avoid those.  If you’re intolerant of carbohydrates, you could avoid eating them, or take drugs to help you overcome your intolerance.  Type 1 diabetics must take insulin.  Insulin’s more optional for type 2’s.  We have 11 classes of drugs to treat type 2 diabetes; we don’t know the potential adverse effects of most of these drugs.  Already, three diabetes drugs have been taken off the U.S. market or severely restricted due to unacceptable toxicity: phenformin, troglitazone, and rosiglitazone. 

Humans need two “essential fatty acids” and nine “essential” amino acids derived from proteins.  “Essential” means we can’t be healthy and live long without them.   Our bodies can’t synthesize them.  On the other hand, there are no essential carbohydrates.  Our bodies can make all the carbohydrate (mainly glucose) we need.

Since there are no essential carbohydrates, and we know little about the long-term adverse side effects of many of the diabetes drugs, I favor carbohydrate restriction for people with carbohydrate intolerance.  (To be clear, insulin is safe, indeed life-saving, for those with type 1 diabetes.)

That being said, let’s think about the Standard American Diet (SAD) eaten by an adult.  It provides an average of 2673 calories a day (not accounting for wastage of calories in restaurants; 2250 cals/day is probably a more accurate figure for actual consumption).  Added sugars provide 459 of those calories, or 17% of the total.  Grains provide 625 calories, or 23% of the total.  Most of those sugars and grains are in processed, commercial foods.  So added sugars and grains provide 40% of the total calories in the SAD.  Remember, we need good insulin action to process these carbs, which is a problem for diabetics.  (Figures are from an April 5, 2011, infographic at Civil Eats.)

Anyone going from the SAD to pure Paleo eating will be drastically reducing intake of added sugars and grains, our current major sources of carbohydrate.  Question is, what will they replace those calories with? 

That’s why I gave a thumbnail sketch of the paleo diet above. Take a gander and you’ll see lots of low-carb and no-carb options, along with some carb options. For folks with carbohydrate intolerance, I’d favor lower-carb veggies and judicious amounts of fruits, berries, and higher-carb veggies and

Will these cause bladder cancer? Pancreatitis?

tubers.  “Judicious” depends on the individual, considering factors such as degree of residual insulin production, insulin sensitivity, the need to lose excess weight, and desire to avoid diabetes drugs.

Compared to the standard “diabetic diet” (what’s that?) and the Standard American Diet, switching to paleo should lower the glycemic index and glycemic load of the diet.  theoretically, that should help with blood sugar control.

A well-designed low-carb paleo diet would likely have at least twice as much fiber as the typical American diet, which would also tend to limit high blood sugar excursions.

In general, I favor a carbohydrate-restricted paleo diet for those with diabetes who have already decided to “go paleo.”  I’m not endorsing any paleo diet for anyone with diabetes at this point—I’m still doing my research.  But if you’re going to do it, I’d keep it lower-carb.  It has a lot of potential.

Are There Any Immediate Dangers for a Person With Diabetes Switching to the Paleo Diet?

It depends on three things: 1) current diet, and 2) current drug therapy, and 3) the particular version of paleo diet followed. 

Remember, the Standard American Diet provides 40% of total calories as added sugars and grains (nearly all highly refined).  Switching from SAD to a low-carb paleo diet will cut carb intake  and glycemic load substantially, raising the risk of hypoglycemia if the person is taking certain drugs.

Drugs with potential to cause hypoglycemia include insulin, sulfonylureas, meglitinides, pramlintide, and perhaps thiazolidinediones.

Who knows about carb content of the standard “diabetic diet”?  Contrary to popular belief, there is no monolithic “diabetic diet.”  There is no ADA diet (American Diabetes Association).  My impression, however, is that the ADA favors relatively high carbohydrate consumption, perhaps 45-60% of total calories.  Switching to low-carb paleo could definitely cause hypoglycemia in those taking the aforementioned drugs.

One way to avoid diet-induced hypoglycemia is to reduce the diabetic drug dose.

A type 2 overweight diabetic eating a Standard American Diet—and I know there are many out there—would tend to see lower glucose levels by switching to probably any of the popular paleo diets.  Be ready for hypoglycemia if you take those drugs.

Paleo diets are not necessarily low-carb.  Konner and Eaton estimate that ancestral hunter-gatherers obtained 35 to 40% of total calories from carbohydrates.  I’ve seen other estimates as low as 22%.  Reality likely falls between 22 and 65%.  When pressed for a brief answer as to how many carbohydrate calories are in the paleo diet, I say “about a third of the total.”  By comparison, the typical U.S. diet provides 50% of calories from carbohydrate.

Someone could end up with a high-carb paleo diet easily, by emphasizing tubers (e.g., potatoes), higher-carb vegetables, fruits, berries, and nuts (especially cashews). Compared with the SAD, this could cause higher or lower blood sugars, or no net change.

A diabetic on a Bernstein-style diet or Ketogenic Mediterranean Diet (both very-low-carb) but switching to paleo or low-carb paleo (50-150 g?) would see elevated blood sugars.  Perhaps very high glucoses.

Any person with diabetes making a change in diet should do it in consultation with a personal physician or other qualified healthcare professional familiar with their case.

Steve Parker, M.D.

Fun Facts!

  • A typical carbonated soda contain the equivalent of 10 tsp (50 ml) of sugar.
  • The typical U.S. adult eats 30 tsp  (150 ml) daily of added sweeteners and sugars.
  • U.S total grain product consumption was at record lows in the 1970s, at 138 pounds per person.  By 2000, grain consumption was up by 45%, to 200 pounds per person.
  • Total caloric sweetener consumption (by dry weight) was 110 pounds per person in the  1950s.  By 2000, it was up 39% to 150 pounds.
  • Between 1970 and 2003, consumption of added fats and oils rose by 63%, from 53 to 85 pounds.  [How tasty would that be without starches and sugars?  Not very.]
  • In 2008, “added fat” calories in the U.S. adult diet were 641 (24% of total calories).

Fun Facts provided by the U.S. Department of Agriculture. 

(The paleo diet is also referred to as the Paleolithic, Old Stone Age, Stone Age, Ancestral, Hunter-Gatherer, or Caveman diet.)